| Date | Location | Result | |
| May 12, 2022 | Jacksonville, Fla. | Kennesaw State 14, Jacksonville State 4 | Box score |
| May 11, 2022 | Jacksonville, Fla. | North Alabama 6, Jacksonville State 3 | Box score |
| May 10, 2022 | Jacksonville, Fla | Jacksonville State 6, Lipscomb 5 | Box score |
| May 07, 2022 | Conway, Ark. | Central Arkansas 2, Jacksonville State 1 | Box score |
| May 06, 2022 | Conway, Ark | Central Arkansas 8, Jacksonville State 0 | Box score |
| May 06, 2022 | Conway, Ark. | Central Arkansas 4, Jacksonville State 3 | Box score |
| May 01, 2022 | Jacksonville, Ala. | Jacksonville State 6, Bellarmine 0 | Box score |
| Apr 30, 2022 | Jacksonville, Ala. | Jacksonville State 6, Bellarmine 0 | Box score |
| Apr 30, 2022 | Jacksonville, Ala. | Jacksonville State 8, Bellarmine 0 | Box score |
| Apr 26, 2022 | Jacksonville, Ala. | Jacksonville State 4, Alabama State 0 | Box score |
| Apr 24, 2022 | Jacksonville, Ala. | Jacksonville State 11, North Alabama 5 | Box score |
| Apr 23, 2022 | Jacksonville, Ala. | North Alabama 7, Jacksonville State 2 | Box score |
| Apr 23, 2022 | Jacksonville, Ala. | North Alabama 9, Jacksonville State 3 | Box score |
| Apr 19, 2022 | Auburn, Ala. | Auburn 9, Jacksonville State 1 | Box score |
| Apr 16, 2022 | Nashville, Tennessee | Jacksonville State 6, Lipscomb 5 | Box score |
| Apr 15, 2022 | Nashville, Tennessee | Lipscomb 8, Jacksonville State 4 | Box score |
| Apr 15, 2022 | Nashville, Tennessee | Jacksonville State 4, Lipscomb 1 | Box score |
| Apr 10, 2022 | Jacksonville, Ala. | Jacksonville State 1, Eastern Kentucky 0 | Box score |
| Apr 09, 2022 | Jacksonville, Ala. | Jacksonville State 7, Eastern Kentucky 0 | Box score |
| Apr 09, 2022 | Jacksonville, Ala. | Jacksonville State 6, Eastern Kentucky 0 | Box score |
| Apr 03, 2022 | Fort Myers, Fla. | FGCU 3, Jacksonville State 0 | Box score |
| Apr 02, 2022 | Fort Myers, Fla. | Jacksonville State 1, FGCU 0 | Box score |
| Apr 02, 2022 | Fort Myers, Fla. | FGCU 5, Jacksonville State 2 | Box score |
| Mar 27, 2022 | Jacksonville, Ala. | Jacksonville State 5, North Florida 4 | Box score |
| Mar 26, 2022 | Jacksonville, Ala. | North Florida 4, Jacksonville State 0 | Box score |
| Mar 26, 2022 | Jacksonville, Ala. | Jacksonville State 2, North Florida 1 | Box score |
| Mar 23, 2022 | SU Softball Stadium | Samford 4, Jacksonville State 2 | Box score |
| Mar 21, 2022 | Jacksonville, Ala. | Jacksonville State 11, Dartmouth 1 | Box score |
| Mar 20, 2022 | Kennesaw, Ga. | Jacksonville State 1, Kennesaw State 0 | Box score |
| Mar 19, 2022 | Kennesaw, Ga. | Kennesaw State 5, Jacksonville State 3 | Box score |
| Mar 19, 2022 | Kennesaw, Ga. | Kennesaw State 6, Jacksonville State 1 | Box score |
| Mar 17, 2022 | Jacksonville, Ala. | SE Louisiana 8, Jacksonville State 5 | Box score |
| Mar 16, 2022 | Jacksonville, Ala. | Jacksonville State 3, Colgate 0 | Box score |
| Mar 11, 2022 | Jacksonville, Ala. | Jacksonville State 5, Samford 1 | Box score |
| Mar 11, 2022 | Jacksonville, Ala. | Jacksonville State 3, Austin Peay 2 | Box score |
| Mar 10, 2022 | Jacksonville, Ala. | Jacksonville State 7, Austin Peay 2 | Box score |
| Mar 10, 2022 | Jacksonville, Ala. | Jacksonville State 4, Samford 1 | Box score |
| Mar 06, 2022 | Starkville, MS | Jacksonville State 6, Furman 2 | Box score |
| Mar 05, 2022 | Starkville, MS | Mississippi State 3, Jacksonville State 2 | Box score |
| Mar 05, 2022 | Starkville, MS | Jacksonville State 13, Alcorn State 1 | Box score |
| Mar 04, 2022 | Starkville, MS | Jacksonville State 5, Alcorn State 2 | Box score |
| Mar 04, 2022 | Starkville, MS | Furman 6, Jacksonville State 4 | Box score |
| Mar 02, 2022 | Jacksonville, Ala. | Jacksonville State 7, ULM 0 | Box score |
| Feb 26, 2022 | Atlanta, Ga. | Georgia State 8, Jacksonville State 3 | Box score |
| Feb 26, 2022 | Atlanta, Ga. | Georgia State 5, Jacksonville State 3 | Box score |
| Feb 23, 2022 | Jacksonville, Ala. | Auburn 10, Jacksonville State 0 | Box score |
| Feb 19, 2022 | Hattiesburg, Miss. | ULM 5, Jacksonville State 2 | Box score |
| Feb 19, 2022 | Hattiesburg, Miss. | Jacksonville State 3, ULM 2 | Box score |
| Feb 18, 2022 | Hattiesburg, Miss. | Jacksonville State 2, Southern Miss 1 | Box score |
| Feb 18, 2022 | Hattiesburg, Miss. | Jacksonville State 7, Houston Baptist 3 | Box score |
| Feb 13, 2022 | MONROE, LA | Jacksonville State 10, Miss Valley State 2 | Box score |
| Feb 13, 2022 | MONROE, LA | Jacksonville State 6, Morehead State 0 | Box score |
| Feb 12, 2022 | MONROE, LA | SFA 11, Jacksonville State 7 | Box score |
| Feb 11, 2022 | MONROE,LA | SIUE 4, Jacksonville State 2 | Box score |
| Feb 11, 2022 | MONROE, LA | Jacksonville State 11, Southern 0 | Box score |