| Date | Location | Result | |
| 03/18/22 | Greenville, SC | Auburn 80, Jacksonville State 61 | Box score |
| 03/05/22 | Jacksonville, AL | Jacksonville 54, Jacksonville State 51 | Box score |
| 03/03/22 | Jacksonville, AL | Jacksonville State 78, Kennesaw St. 67 | Box score |
| 02/26/22 | Jacksonville, AL | Jacksonville State 69, North Ala. 52 | Box score |
| 02/23/22 | Jacksonville, AL | Jacksonville State 81, Eastern Ky. 68 | Box score |
| 02/20/22 | Louisville, KY | Jacksonville State 82, Bellarmine 67 | Box score |
| 02/16/22 | Nashville, TN | Jacksonville State 78, Lipscomb 67 | Box score |
| 02/12/22 | Jacksonville, AL | Central Ark. 72, Jacksonville State 62 | Box score |
| 02/09/22 | DeLand, FL | Stetson 63, Jacksonville State 57 | Box score |
| 02/05/22 | Jacksonville, AL | Jacksonville State 64, Jacksonville 58 | Box score |
| 02/03/22 | Jacksonville, AL | North Florida 88, Jacksonville State 76 | Box score |
| 01/29/22 | Lynchburg, VA | Jacksonville State 77, Liberty 67 | Box score |
| 01/27/22 | Kennesaw, GA | Jacksonville State 70, Kennesaw St. 64 | Box score |
| 01/24/22 | Jacksonville, AL | Jacksonville State 65, Bellarmine 60 | Box score |
| 01/22/22 | Jacksonville, AL | Jacksonville State 79, FGCU 71 | Box score |
| 01/18/22 | Conway, AR | Jacksonville State 86, Central Ark. 81 | Box score |
| 01/15/22 | Richmond, KY | Jacksonville State 76, Eastern Ky. 65 | Box score |
| 01/11/22 | Jacksonville, AL | Jacksonville State 88, Lipscomb 83 | Box score |
| 01/08/22 | Florence, AL | Jacksonville State 65, North Ala. 55 | Box score |
| 12/28/21 | Jacksonville, AL | Jacksonville State 123, Carver 59 | Box score |
| 12/21/21 | Little Rock, AR | Jacksonville State 87, Little Rock 67 | Box score |
| 12/18/21 | Tuscaloosa, AL | Alabama 65, Jacksonville State 59 | Box score |
| 12/15/21 | Jacksonville, AL | Jacksonville State 66, FIU 59 | Box score |
| 12/13/21 | Jacksonville, AL | Jacksonville State 110, LaGrange 80 | Box score |
| 12/08/21 | Richmond, VA | VCU 66, Jacksonville State 52 | Box score |
| 12/04/21 | Jacksonville, AL | South Alabama 74, Jacksonville State 64 | Box score |
| 11/27/21 | Elon, NC | Jacksonville State 93, Elon 81 | Box score |
| 11/24/21 | Nassau, Bahamas | Jacksonville State 72, Drexel 64 | Box score |
| 11/22/21 | Nassau, Bahamas | Valparaiso 78, Jacksonville State 70 | Box score |
| 11/16/21 | Troy, AL | Troy 69, Jacksonville State 65 (3OT) | Box score |
| 11/13/21 | Jacksonville, AL | Jacksonville State 70, Alabama A&M 47 | Box score |
| 11/09/21 | Wichita, KS | Wichita St. 60, Jacksonville State 57 | Box score |